Castleman Disease Radiology Qradiology


Radiology of Castleman disease the pivotal role of imaging in diagnosis, staging, and response

Castleman disease is a rare disorder that involves an overgrowth of cells in your body's lymph nodes. The most common form of the disorder affects a single lymph node, usually in the chest or abdomen. This form is called unicentric Castleman disease. Multicentric Castleman disease, or MCD, affects multiple lymph nodes throughout the body.


Castleman Disease Radiology Qradiology

Castleman's disease, also known as angiofollicular or benign giant lymph node hyperplasia, is an uncommon benign lymphoproliferative disorder [ 1 - 3 ]. Pathologically, two major histologic types are recognized: the hyaline-vascular type and the plasma cell type.


Castleman Disease The Great Mimic RadioGraphics

Castleman disease has been associated with the human immunodeficiency virus, lymphoma, POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) syndrome, paraneoplastic pemphigus, and plasma cell dyscrasias. Aggressive forms of Castleman disease with systemic manifestations may occur.


Castleman disease Radiology Case

Castleman disease is a non-neoplastic, non-clonal lymph node hyperplasia which can be idiopathic or associated with HIV, lymphoma, POEMS and other disorders. It commonly presents as avidly-enhancing adenopathy. Most cases (90%) are hyaline vascular, which occurs in younger patients, is unicentric, asymptomatic, and follows a benign course.


Castleman disease unicentric vascular hyaline type Image

Castleman disease, also known as angiofollicular lymph node hyperplasia or giant lymph node hyperplasia, is an uncommon benign B-cell lymphoproliferative condition. It can affect several regions of the body but is commonly described as a solitary mediastinal mass. There are two distinct subtypes of Castleman disease: unicentric Castleman disease


68GaDOTATATE and 18FFDG in Castleman Disease Clinical Nuclear Medicine

Castleman disease is a rare, benign disorder of the lymph nodes that should be included in the differential diagnosis of anterior mediastinal masses. It is a lymphoproliferative disorder and is also known as angiofollicular lymph node hyperplasia, benign giant lymphoma, giant lymph node hyperplasia, and follicular lymphoreticuloma 1-3.


Castleman disease Image

Castleman disease is a rare disease of lymph nodes and related tissues. It is also known as giant lymph node hyperplasia and angiofollicular lymph node hyperplasia. It was first described by Dr. Benjamin Castleman in the 1950s 1-3. Neck involvement in Castleman disease accounts for approximately 14% of all cases of the disorder 4.


Castleman disease. Contrastenhanced chest CT scan shows matted... Download Scientific Diagram

Castleman disease (CD) is a rare, nonclonal lymphoproliferative disorder having distinct subtypes depending on its etiology, pathology, and clinical presentation. It can affect lymph nodes of any body region, imitating both benign and malignant malformations, including the neck, chest, abdomen, and pelvis.


Castleman Disease of the Thorax Clinical, Radiologic, and Pathologic Correlation From the

Castleman disease in the abdomen or pelvis in the radiology literature is generally limited to case reports. The two principal histologic types of Castleman disease are hyaline-vascular and plasma cell types. A rare and potentially fatal, systemic form of Castleman disease has also been described [2]. The cytology and core his-


Castleman disease Radiology Reference Article Radiology, Disease, Systemic

Castleman Disease (CD) is a rare entity that typically presents as an enhancing nodal mass in the mediastinum or head and neck region on computed tomography (CT). It may manifest as unicentric or multicentric regions of lymph node enlargement.


Castleman disease Image

First described in 1954 [], Castleman disease (also known an angiofollicular lymph node hyperplasia and giant lymph node hyperplasia) is a rare, usually benign process of unknown cause, characterized by lymphocyte proliferation.Castleman disease is most frequently described in the radiology and pathology literature as located in the mediastinum but may be found in other anatomic locations.


Castleman disease Cases in Radiology YouTube

Castleman disease is usually diagnosed by exclusion and histopathology, our patient has no history of HIV infection and shows multiple enlarged inguinal and intrabdominal lymph nodes with homogenous enhancement in the post-contrast study, no arborising calcification, the differential diagnosis includes infective, reactive causes, and neoplastic.


Figure 3 from Multicentric Castleman's disease manifesting in the lung clinical, radiographic

PURPOSE: To correlate the radiologic manifestations of thoracic Castleman disease with the clinical and histopathologic features. MATERIALS AND METHODS: The clinical, surgical, and histopathologic records; chest radiographs; and computed tomographic (CT) and magnetic resonance (MR) images in 30 pathologically proved cases of thoracic Castleman disease were reviewed. RESULTS: Patients with.


Castleman disease Radiology Reference Article Radiology, Disease, Pleural

Castleman disease elevated levels of anti-VEGF Minor criteria: organomegaly ( hepatomegaly , splenomegaly , or lymphadenopathy) extravascular volume overload (edema, pleural effusion, or ascites) endocrinopathy (adrenal, thyroid, pituitary, gonadal, parathyroid, or pancreatic)


Castleman disease Image

Castleman disease (CD), also known as giant lymph node hyperplasia, lymphoid hamartoma, or angiofollicular lymph node hyperplasia, is a group of uncommon lymphoproliferative disorders that share common lymph node histological features. The disease was first described in a single case in 1954 [ 1 ], followed by a small series of cases in 1956 [ 2 ].


Castleman Disease The Great Mimic RadioGraphics

Three distinct subtypes of Castleman disease have been described in literature, namely unicentric Castleman disease (UCD) human herpesvirus 8 associated multicentric Castleman disease (HHV-8-associated MCD) and idiopathic multicentric Castlema.